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Tuesday, November 12, 2019
Calquence: Uses, Dosage, Side Effects

Calquence: Uses, Dosage, Side Effects

Posted in: Medications List
Sun, Mar 31, 19, 04:11, 8 Months ago
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Calquence

CALQUENCE (acalabrutinib) is associate degree substance of Bruton amino acid enzyme (BTK). The formula for acalabrutinib is C26H23N7O2, and therefore the mass is 465.51. The chemical name is 4--N-(pyridine-2-yl)benzamide.

Acalabrutinib could be a white to yellow powder with pH-dependent solubility. it's freely soluble in water at pH values below three and much insoluble at pH values on top of six.

CALQUENCE capsules for oral administration contains a hundred mg acalabrutinib and therefore the following inactive ingredients: silicified crystalline polysaccharide, part pregelatinized starch, metal stearate, and metal starch glycolate. The capsule shell contains gelatin, pigment, yellow iron chemical compound, FD&C Blue two and is imprinted with edible black ink.

 

Generic Name: acalabrutinib capsules

 

Calquence Indications:

CALQUENCE is indicated for the treatment of adult patients with mantle cell cancer (MCL) World Health Organization have received a minimum of one previous medical care.

This indication is approved beneath accelerated approval supported overall response rate [see Clinical Studies]. continuing approval for this indication is also contingent upon verification and outline of clinical profit in substantiating trials.

 

Calquence Dosage:

The counseled dose of CALQUENCE is a hundred mg taken orally about each twelve hours till sickness progression or unacceptable toxicity.

Advise patients to swallow capsule whole with water. Advise patients to not open, break or chew the capsules. CALQUENCE is also soft on or while not food. If a dose of CALQUENCE is lost by over three hours, it ought to be skipped and therefore the next dose should be taken at its often regular time. further capsules of CALQUENCE shouldn't be taken to create up for a lost dose.

 

Calquence Side Effects:

The following adverse reactions are mentioned in bigger detail in alternative sections of the labeling:

Hemorrhage 
Infection 
Cytopenias 
Second Primary Malignancies 
Atrial Fibrillation and Flutter

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